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Marczylo EL, Amoako AA, Konje JC et al (2012) Smoking induces differential miRNA expression in human spermatozoa: a potential transgenerational epigenetic concern

even beneficial insects like bees and lady bugs

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The people of the Caribbean islands snorted a powder containing 50% tobacco, and those living in what is now Guyana (northern South America) used to boil tobacco down to a liquid