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All protocols require informed consent, medical oversight, and realistic expectations about potential outcomes

Poor Coordination : Tasks that require fine motor skills, such as buttoning a shirt or walking in a straight line, become more difficult

In addition, the studies differ in duration, dose escalation, participant characteristics, number-based estimands, and whether the drug was used alone or in combination

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Over time, these pathways can become disrupted by stress, aging, and environmental toxins

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