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The harmful substances in cigarette smoke can lead to inflammation and fluid retention, particularly around the eyes and cheeks

Increased levels of matrix metalloproteinase (MMP)890 and MMP1 messenger ribonucleic acid91in skin tissues, and higher circulating MMP9 levels81, 92 are found in smokers, resulting in enhanced extracellular matrix degradation, which could also be part of the mechanisms for the decrease of collagen

E-liquid (which can contain nicotine, flavorings, and a base like propylene glycol or vegetable glycerin)

However, you wont get the same combustion effects that youd get from traditional cigarettes

An electronic cigarette is a product that transforms a liquid containing nicotine into an aerosol that is inhaled via a mouthpiece. This definition would avoid the recent confusion regarding devices using other drugs. The authors also ask the CDC to correct misinformation regarding the role of e-cigarettes in youth cigarette use