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Although tobacco additives are generally screened for their direct toxicity, there is virtually no assessment of the impact additives have on smoking behaviour or other undesirable external consequences

There will be more than four-thousand runners this year, which may set a new participation record.

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Possible side effects of the nicotine patch include: skin irritation such as redness or itching dizziness racing heart rate sleep problems or unusual dreams, which are more common with the 24-hour patch headache nausea muscle aches and stiffness Some side effects, such as a racing heart rate, could mean the nicotine dose is too high

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