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Burning fossil fuels has released billions of tons of carbon dioxide pollution into the atmosphere, making that blanket thicker and trapping more heat, leading to global warming. Condition #1 then used the blanket metaphor + explained how we know that climate change is not naturally caused

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Conversely, airway instillation of recombinant CXCL5 (rCXCL5) in CS-exposed Nlrp6 -/- mice was sufficient to restore most of CS-induced BALF neutrophil influx and MPO levels ( Figures S3F, G ), demonstrating that CXCL5 is a major neutrophil chemokine in CS-induced inflammation