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These findings informed human PET studies using the HDAC tracer [11C] Martinostat, which confirmed elevated HDAC expression in the brains of chronic drinkers

Miranda VC, Barroso-Sousa R, Glasberg J, Riechelmann RP

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The development of the present therapeutic medicines in clinic mainly targets the discovered pharmacological targets, mainly focusing on the key receptors or enzymes

An overview on pharmaceutical applications of phosphodiesterase enzyme 5 (PDE5) inhibitors

Kosek E, Cohen M, Baron R, Gebhart GF, Mico JA, Rice AS, et al