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In vivo studies Pulmonary toxicity A PMI study on chronic exposure of A/J Mice for 18 months to IQOS smoke showed that IQOS significantly reduced toxicity and carcinogenicity on red blood cell profile, liver function, lung inflammation, emphysematous, and histopathological changes compared to CS in respiratory tract organs 41

Nausea is the most commonly reported

A Cochrane review by Farley et al

doi: 10.1093/ntr/ntw140 43

Branch, Taylor (1988)

It is foreseeable that the future EU e-cigarette regulatory system will have a new set of rules, which is particularly noteworthy for Chinese e-cigarette manufacturers and brands expanding overseas