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Nicotine is highly addictivecomparable to cocaine, heroin, and alcoholand works by triggering dopamine release in the brains reward center

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The findings are anticipated to yield novel perspectives and contribute to formulating preventive and therapeutic approaches for early-onset OA management

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Hence, the FDA recommends close monitoring of neuropsychiatric symptoms in patients receiving bupropion and to stop bupropion therapy if any contraindications were to be found ( 92 )