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Careful TDM for CLO should be performed prior to dose adjustmentto reduce the increased risk of smoking cessation induced side effects, especially for older patients receiving multiple medications
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Cannabis is associated with some minor side effects, but no deaths exclusively due to cannabis use have ever occurred
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Conclusions Despite a decreasing trend for smoking in some developed countries over the last decade, smoking worldwide is still on the increase, particularly in developing nations (Office for National Statistics, 2010
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