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We are entirely dependent on dietary intake or supplementation, and even with adequate dietary intake, absorption can be impaired by a range of factors including age-related changes to stomach acid production, certain medications, and digestive conditions

Azathioprine or 6-MP can be considered, but usually neither is recommended for induction therapy because the data on efficacy are limited and the onset of action is slow

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While aging is inevitable, the rate at which these changes occur varies significantly between individuals

Peristalsis of the esophageal body then propels the food toward the stomach

Mechanisms of action of the peptide remain under research and scientists are striving to comprehend the interactions of the peptide with other biological systems under varied conditions of experimental study