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Cytochrome P450 2D6 Cloud Data Centers " Sor Juana Inés deCytochromes are proteins &ltthat catalyze electron transfer reactions of well known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, Function, Regulation, and Polymorphism&lt reviews