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Tirzepatide is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and should not be used during pregnancy due to potential fetal harm

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26 A review of 17 clinical studies of various trial designs, including pro- and retrospective, concluded that B12, particularly subcutaneously injected mB12 [methyl-B12], improves metabolic abnormalities in ASD along with clinical symptoms

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