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Neurodegenerative diseases Neurons cannot dilute damaged organelles and cellular waste through cell division, implying the great need for an efficient intracellular clearance system 121,122

In India's high-UV environment, increased photosensitivity is particularly problematic UV exposure is already the primary driver of most pigmentation concerns, and an ingredient that worsens UV sensitivity while treating UV-induced darkening creates a difficult practical balance

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Innovative therapeutic strategies, including microbial therapeutics (such as probiotics, prebiotics, and synbiotics), natural products (such as neohesperidin, isoquercitrin, and polysaccharides), and fecal microbiota transplantation, have been proposed to restore microbial balance and improve kidney function