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Despite the leaky colon, as determined by electrophysiological measurements and presence of rectally administered FITC-dextran into blood circulation, Cl-2TG mice demonstrated resistance against acute or chronic colitis induced by administering the DSS in drinking water

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This effect was not restricted to Venetoclax, as knockout or pharmacologic inhibition of ABCC1 also sensitized AML cells to other BH3 mimetics, including ABT-737, Navitoclax and the novel BCL-2/BCL-xL inhibitor AZD-4320

Based on the current scientific evidence, antibiotic therapy may be a potential intervention to prevent colon carcinogenesis in H