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Zhong et al., 2020

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Lauer S.A., Grantz K.H., Bi Q., Jones F.K., Zheng Q., Meredith H.R., Azman A.S., Reich N.G., Lessler J

Among the findings of altered brain structure and function in patients with depression, the most consistent is structural deformation and impaired function in the hippocampus and prefrontal cortex (PFC) [51]

Notwithstanding the promising findings, the existing clinical literature exhibits significant inconsistencies

The data is earlier-stage and most of the human work comes from outside the U.S