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doi: 10.1126/science.1523409

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However, GHK has some unique characteristics which may be attributed to its importance as a copper-regulating compound on a cellular level

149 The traditional Chinese medicine formula XZTZ acts via SIRT1 to downregulate NLRP3 and GSDMD, reduce pro-inflammatory cytokines, and promote macrophage polarization from M1 to M2, improving the hepatic immune microenvironment

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