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RXR agonists are also effective in the treatment of some neuropathies, such as Alzheimers disease 61 and Parkinsons disease in animal models 62

27 ManosJ.ArthurJ.RoseB.BellS.TingpejP.HuH.et al (2009)

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Their inherent properties, including low systemic toxicity, site-specific delivery, and the capacity to penetrate biofilm matrices, enable improved local drug concentration and reduce recurrence rates [205]

391 Conversely, a smaller study involving 82 heart failure patients indicated that long-term allopurinol administration was associated with an improvement in left ventricular function

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