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Experimental validation of broad-spectrum antivirals in viral infection assays The antiviral activity of the identified compounds phenformin, atpenin A5, SR13800, and scyllo-inositol was first tested in the lung-cancer cell line Calu-3 and the colon-cancer cell line CaCo-2 infected with SARS-CoV-2 (Fig
Searches of clinicaltrials.gov for BPC-157 return only a small number of registered studies, predominantly observational or compounded-product registries rather than randomized interventional trials with peer-reviewed protocols and pre-registered outcome measures
The first obstacle lies in the intrinsic 'undruggability' of these transcription factors
These agents exhibit translational potential across cancers, metabolic and infectious diseases, cardiovascular injury, and neurodegeneration