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I was nervous initially but once I spoke with Dr

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Later it was also shown that the MRAP protein is necessary not only for the trafficking of the receptor to cell surface, but also for conformational changes necessary for the binding of the ACTH ligand either by influencing ACTH ligand binding or by facilitating the interaction of the Gas protein with the receptor, or both (54)

C.: American Chemical Society

One mechanistic avenue suggested by Fu et al

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