PLOS One 11, e0161759
The limitation is injection volume: if your target dose now requires more than 1.5mL per injection, you must either split the dose across two injection sites, reduce the dose, or discard the vial and reconstitute a new one correctly
Benefit 1
Your refrigerator built-in thermometer, if it even has one, is often inaccurate
Bottom line: If you want to maximize the effects of glutathione, quality and consistency are more important than taking the highest possible dose

Your doctor will conduct a comprehensive clinical assessment including: Detailed medication and supplement history , including over-the-counter vitamins and injections Review of symptoms suggesting liver, kidney, or haematological disease Physical examination for hepatomegaly, splenomegaly, jaundice, or lymphadenopathy Additional blood tests , such as full blood count, liver function tests, renal function, and inflammatory markers Depending on initial findings, further investigations may include: Liver ultrasound or imaging if hepatic pathology is suspected Haematology referral for blood film examination, bone marrow biopsy, or specific tests for myeloproliferative disorders Measurement of holotranscobalamin or methylmalonic acid if functional B12 status needs clarification despite high total B12 Targeted investigations based on clinical findings and following NICE guidance for suspected serious conditions Treatment focuses on addressing the underlying cause rather than the elevated B12 itself
