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Menadione metabolism to thiodione in hepatoblastoma by scanning electrochemical microscopy

It was more effectively activated by elevated levels of GSH in H1299 lung cancer cells than that in normal lung fibroblasts WI38 cells, releasing reactive alkoxyamines to capture AP sites, blocking APE1 repair, and leading to lung cancer cell death in vitro

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Evidence of the Effects of Supplemental or Dietary Vitamin C on the Prevention of Cataracts in Humans Given the role of oxidative stress in cataractogenesis, it is not surprising that the role of antioxidant intake and cataract in human populations has been extensively studied [6,8,110]