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383,384 Once IL-6 binds to IL-6R, the IL-6/IL-6R complex is able to activate its coreceptor gp130, which initiates downstream pathways, including the JAK/STAT3, PI3K/AKT, and MAPK pathways

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Each injury is accompanied by increasing pain, swelling, bruising, or limited mobility, which is why quick and effective therapy is so important to restore our freedom of movement and quality of life