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These data are clinically relevant as in vitro cisplatin resistance has been reported to be predictive of cancer chemoresistance in patients 38 , and resistance to platinum-based chemotherapy is one of the main factors contributing to poor patient prognosis 48

Common signs of withdrawal include: Smelling cigarette smoke Craving for cigarettes Handling lighters and matches Feeling like you need to do something with your hands The best way to manage these symptoms is to distract yourself

This may result in the exclusion of relevant interventions published in other than English

When this happens, the mitochondrial quality control system initiates a response, which includes eliminating unrepairable mitochondria through fission and mitophagy, maintaining mitochondria function through fusion, and filling the energy metabolism gap via mitochondrial biogenesis

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