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The cells were cultured in normal-glucose medium for 48 h and then treated with the following media: (1) low glucose group (LG) (5.5 mM)

In the liver and brain, some amount of G6P is also used by the pentose phosphate pathway (PPP), to provide NADPH for lipid biosynthesis, operation of antioxidant systems, and ribylose-5-phosphate for DNA reparation under stress conditions (Rajas et al., 2019)

Hepat Mon 10:1216 Kim E, Viatour P (2020) Hepatocellular carcinoma: old friends and new tricks

And it suppresses glucagon release, which helps regulate blood sugar after meals

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