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As wound healing is essential to tissue integrity and overall health, the care and management of chronic wounds in aging populations have become a critical public health concern, annual cost of treating chronic wounds, including various ulcers, are estimated to reach up to $96 billion in the U.S

In addition, we further concluded that potential lifestyle interventions and pharmacological approaches, including antioxidants, RAS inhibitors, finerenone and hypoglycemic agents, such as sodium-glucose cotransporter-2 inhibitors, liraglutide and pioglitazone may exert the preservation of cognitive function

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References: [1] Orrick, Herrington & Sutcliffe LLP