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Autret E, Dutertre JP, Breteau M et al , Pharmacokinetics of paracetamol in the neonate and infant after administration of propacetamol chlorhydrate

A key factor in the experimental protocol is the use of Matrigel as an ECM scaffold, because of its heterogeneity and its poorly defined composition

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GL is taken up from blood into hepatocytes primarily by human organic anion-transporting polypeptides OATP1B1 and OATP1B3 (Oatp1b2 in rats) (Ploeger et al., 2001)