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It is not appropriate during pregnancy or breastfeeding, in active cancer, or in patients with severely uncontrolled metabolic disease without specialist coordination

Not FDA-approved for any human use

Both undernutrition and obesity can disrupt this axis

Injection dosages are usually around 1,000 mcg while oral supplement dosages can range from 50 to 5,000 mcg

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Adaptive thermogenesis with weight loss in humans