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This article builds on the evidence presented in the TKS, with a greater level of detail intended for a lung-specialist audience

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After much internal debate, the anti-smoking lobby has mostly come out against them

The companies most often referred to collectively as Big Tobacco Philip Morris International (PMI), British American Tobacco (BAT), Imperial Brands and Japan Tobacco International (JTI) have all been hit over the years with scandals involving smuggling and unethical advertising

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The ability to control the flow of power to the atomizer and the the ability to fully shut off the pen from operation are features that some users like to have