Other notable adverse effects include: Hypoglycemia : Low risk when used as monotherapy, but increased when combined with insulin or sulfonylureas Injection site reactions : Erythema, pruritus, or discomfort in approximately 2% to 4% of patients Fatigue and dizziness : Reported in 5% to 8% of participants Increased heart rate : Mean increases of 2 to 4 beats per minute observed Serious adverse events were uncommon but included acute pancreatitis (approximately 0.2% incidence), gallbladder disease including cholecystitis and cholelithiasis (0.6% in diabetes trials and up to 2.5% in weight management trials, associated with rapid weight loss), and acute kidney injury, typically in the context of severe dehydration from gastrointestinal symptoms
Additionally, Fe 3+ can be reduced to Fe 2+ via oxidizing GSH, accompanying the production of OH through a Fenton-like reaction
c bit khng cha du khong Glutathione mt hot cht chng oxy ha liu lng cao lm sng da hiu qu nhanh, lm m thm nm an ton cho da
Necrostatin-1 and necroptosis inhibition: pathophysiology and therapeutic implications
GLOBAL GLUTATHIONE MARKET SIZE, BY TABLETS, BY REGION, 2018-2032 (USD MILLION) TABLE 65
Microglia are widely distributed throughout the CNS and account for approximately 515% of all brain cells [21]
