Overall, our findings support the robustness of the proteomic dataset, as two of the six proteinsGAPDH and CPB2showed strong concordance between DIA-MS and ELISA
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The IL-17 secreted by these cells binds to IL-17 receptors (IL-17Rs) expressed in midbrain neurons, inducing neuronal death through the upregulation of NF-B and downstream signaling pathways, as demonstrated in human iPSC-derived neuronal models
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Aged skin is characterized by an atrophic epidermis, with senescent keratinocytes and melanocytes and a flattened basement membrane