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Hence, given the low expression of PKM2 in neurons, chemicals targeting PKM2 may not affect the physiological functions of neurons, avoiding unexpected side effects

J Orthop Res 2003;21:976-983

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5.2.4 Metal-based platforms for ferroptosis-ICB synergy A hydrazine/Cu/Fe/indocyanine green (TCFI) coordination nanocomplex exemplifies nanotechnologys capacity to integrate multiple therapeutic modalities