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As the autoimmune attack progresses and the number and function of cells decline, the risk of developing overt T1D increases

In order to reduce the age-related damage of oocytes caused by prolonged culture in vitro , it is necessary to find an agent that has no negative effect on oocyte development and can effectively delay the aging damage caused by the accumulation of ROS

Importantly, folic acid should not be given alone before B12 deficiency is excluded or treated, as this can mask anaemia while allowing neurological damage to progress

Finland now maintains moderate selenium levels (60-80 g/day) through selenium-enriched fertilisers [24]

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