It has been found that persistent use of PPIs causes nutritional deficiencies (magnesium, vitamin B12, and iron), kidney damage, osteoporosis, rhabdomyolysis, anemia, thrombocytopenia (Heidelbaugh and Inadomi 2006), and neurological ailments (Ortiz-Guerrero et al
Urolithins are microbial metabolites derived from ellagitannins and ellagic acid, polyphenols naturally present in foods such as berries, pomegranate, and nuts (25)
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Harlie M
Children's requirements are lower and increase with age: infants aged 0-6 months have a safe intake of about 0.3 g daily, those aged 712 months need 0.4 g daily, children aged 13 years require 0.5 g, those aged 46 years need 0.8 g, and children aged 710 years should receive 1.0 g daily