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Another significant study highlighted that ASN90 (also referred to as ASN-120290 or ASN-561), a novel OGA inhibitor, improved survival, respiratory function, and motor skills in the JNPL3/P301L mouse model of AD, attributed to an increase in O-GlcNAcylated Tau and a reduction in neurofibrillary tangles [183]

Upon passing the extracted GSH from the DBS through a PD MiniTrap G-25 Sephadex column, all proteins eluted in the first three fractions (see supporting information and Fig

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None had a placebo control group

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