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For example, caspase-8 cleaves GSDMC, GSDMD, and GSDME (Orning et al., 2018

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During parasite infection, macrophages primarily display an anti-inflammatory M2-like phenotype, as characterized by the expression of specific effector molecules, such as arginase-1 (Arg1), Ym1 and resistin-like molecules (RELM)