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Unlike plasma, CSF is not separated from the brain by the bloodbrain barrier

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Aloe vera mitigates dextran sulfate sodium-induced rat ulcerative colitis by potentiating colon mucus barrier

70 Moreover, in tissues of PDA patients, lactylation of TFEB at lysine 91 has been identified, which prevents its ubiquitination and proteasome degradation by hindering its interaction with the E3 ubiquitin ligase WWP2, enhancing TFEB activity and autophagy flux, which promotes pancreatic cancer progression

For a detailed description please refer to the Supplementary methods

What Recategorization Actually Means It is important to understand what this regulatory shift does and does not change