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& Levitt, P

Clinically, there is much interest in understanding the role that G6PD deficiency and an associated aberrant innate immune effector response might play in childhood sepsis

Clinics in Dermatology, 28, 412-419

Notably, activators of SIRT1, such as metformin, have demonstrated the ability to inhibit Th17 cell differentiation and downregulate IL-17A and RORt levels by promoting STAT3 deacetylation (Hamaidi and Kim, 2022)