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A climate of generalized chronic inflammation is then created, characterized by an increase in several inflammatory markers (IL-6, CRP, ICAM) and the recruitment of immune cells to the surface of blood vessels, two phenomena that contribute to the development of atherosclerosis

Joe's car is a symbol of his desire for a bigger more glamorous life and, when he watches it being towed away, he is seeing more than his car being taken from him after all he has already revealed that losing his car would be like having his legs cut off

Bedaquiline does not induce or inhibit major CYP isoenzymes, namely, CYP1A2, CYP2C9, CYP2C19, or CYP2D6 at clinically relevant concentrations, minimizing the risk of CYP450-related interactions (Mesens et al., 2010)

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