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The other part of the hydrolyzed glutathione (GSH) molecule cysteinyl-glycine is transported back inside the cell and broken down further by nonspecific dipeptidases into cysteine and glycine ready providing substrates for glutathione (GSH) resynthesis

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Tronci L, Serreli G, Piras C, Frau DV, Dettori T, Deiana M, et al

It is important to note that such violations may suggest low oral bioavailability (due to high molecular weight or excessive lipophilicity), solubility limitations (reflected in Log S and TPSA values, leading to poor dissolution), inadequate permeability, an increased risk of toxicity or adverse effects, and/or a reduced likelihood of clinical success

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This introduction phase establishes baseline tolerance and reveals any underlying sensitivity to copper peptides specifically