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The ROS scavenging property of Sp was also replicated in the Drosophila models knocked-down for essential antioxidant enzymes catalase and glutathione peroxidase, where neuronal cells of 15 days AEL flies genetically expressing a redox biosensor, roGFP showed reduced fluorescence under Sp treatment (Fig

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For example, ginsenosides has been shown to increase GPX, SOD and catalase (CAT) activity and restore GSH levels, while inhibiting ERK and JNK MAPK pathways (Park et al., 2012