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Nine rats were randomly chosen from each group for gingival tissue vascular permeability measurements, whereas the remaining animals were used for soft tissue histology

doi: 10.1371/journal.pone.0038760

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

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Gastrointestinal symptoms such as mild digestive discomfort affect some patients, though severe reactions are uncommon