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1, 14, 15 Types of birth control known to deplete Vitamin B6 10* Estradiol, Estradiol combinations, Ethinyl Estradiol, Ethinyl Estradiol combinations, Levonorgestrel, Norethindrone, Estrogens (conjugated, synthetic, and esterified), Estrogen combinations, Estropipate Example B6 depletion symptoms 10 Poor sleep Altered mobility Low mood Nausea B12 deficiency and birth control pills Vitamin B12 is critical for proper metabolism converting food to energy