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Despite correcting his severe B12 and iron deficiency with supplementation, this child remained delayed 7 months after treatment and upon MRI, still showed signs of inadequate myelination, suggesting that he may never achieve full neurological function

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Tier 3 patients often experience significant improvements in energy levels and brain fog within 2-4 weeks, with substantial weight loss and metabolic improvements within 8-12 weeks, and continued progress over 6-12 months

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