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Methylcobalamin injections are often recommended for these patients because they bypass the digestive system and deliver B12 directly into the bloodstream
However, the pediatric acute liver failure study group has found that in chronic exposure to APAP (in contrast to a single toxic dose), younger patients (median age, 3.5 years) experienced a greater level of hepatotoxicity comparative to older adolescent patients (median age 15.2 years) who were more likely to experience hepatotoxicity from a single toxic dose (Rumack et al., 1981)
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The agency cited immunogenicity concerns, saying there was limited data on the quality, stability and consistency of the compounds
However, it is essential to speak with we professionals before this treatment