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doi: 10.1111/epi.13925 [10] Frey N, Bircher A, Bodmer M et al

The absence of P-gp was verified by Western blot using P-gp-directed monoclonal antibodies, C219 and C494 mAbs which bind different epitopes in P-gp ATPase domain conserved in human and hamster [26]

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This phenomenon has been widely associated with the development and progression of various chronic and degenerative diseases, including diabetes, cardiovascular diseases, neurodegeneration, cancer, and premature aging [5, 6]