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gRNA sequences (Supplementary Table 33) were obtained from Synthego and oligos with 5 overhang for cloning into lentiCRISPRv2 were manufactured by Thermo Fisher Scientific

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In rodent studies, it has reduced neuronal damage from hippocampal ischemia-reperfusion injuries and reduced the effects of traumatic brain injury lesions

Moreover, there is emerging evidence for the translocation of PET MNPs from the gut to distant organs, highlighting potential systemic consequences of oral exposure

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From a biochemical perspective, L-carnitine plays a key role in the transport of long-chain fatty acids into the mitochondria the powerhouse of the cell where they are oxidized to produce energy