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10.1146/annurev-nutr-071811-150740 Annu

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Based on immunological studies, - glucans considered active compounds to induce immune effects and initiate anti-microbial immune responses and anti-tumor activities

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(2) the specific CI inhibitor IACS-010759 was recently reported to promote neurotoxicity, making this an unattractive agent for combination therapy in CRC given the neurotoxicity long-recognized with oxaliplatin treatment 51

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