See Pros and Cons of Using PRP for Tendon Injuries Prolotherapy This treatment involves administering small amounts of a medicated solution, such as dextrose or saline, into the rotator cuff tissue(s) over a period of several weeks with the goal of inducing tissue regeneration, promoting healing, and reducing pain
This strategy provides both high local concentration and broader systemic support
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As a beneficial property, inhibition of the inflammatory response did not impair wound healing and did not induce failed collagen synthesis (Mikus et al., 2001