Researchers became interested in combining these peptides when early studies revealed their complementary pharmacokinetics: Ipamorelin peptide provides an immediate GH pulse (peaking within 40 minutes), while CJC-1295 sustains release over several hours
This effect is thought to be mediated through GLP-1 receptors in the cardiovascular system and is generally not clinically significant, though patients with certain arrhythmias or those sensitive to heart rate changes should be monitored
Salven P, Lymboussaki A, Heikkil P, Jskela-Saari H, Enholm B, Aase K, et al
Full and distended stomach, and vascular response
Epithelial cells have a variety of functions and are closely interconnected [8, 9, 14, 15]
Acta Physiol Scand Suppl 1989