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Patients who are pregnant or planning to become pregnant should inform their healthcare provider

IDH2 and IDH3 are localized in the mitochondrial matrix

Mitochondrial-targeted protective potential of elamipretide for the in vitro production of porcine embryos

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More studies using genetic models such as APP null mice or -secretase beta-site APP-cleaving enzyme 1 (BACE1) null mice display a range of dysfunctions such as lowered synaptic plasticity, restricted neurogenesis and cognitive deficits (Cai et al., 2023)

Jet fuel exposure may also increase oxidative stress that can impact auditory function